Cytotoxic Constituents from the Stem Bark of Alvaradoa amorphoides

Sergio R. Peraza-Sanchez

doi:10.29356/jmcs.v59i3.37

Cytotoxic Constituents from the Stem Bark of Alvaradoa amorphoides

Authors

Sergio R. Peraza-Sanchez Centro de Investigación Científica de Yucatán (CICY)

DOI:

https://doi.org/10.29356/jmcs.v59i3.37

Keywords:

Alvaradoa amorphoides, cytotoxic activity, antiproliferative activity, acetylenic compound

Abstract

The chemical study of Alvaradoa amorphoides led to the isolation of four major constituents: chrysophanol (1), β-sitosterol (2), atraric acid (3), and 17-octadecen-6-ynoic acid (4). All compounds were evaluated on in vitro cytotoxic and antiproliferative assays. Atraric acid and 17-octadecen-6-ynoic acid showed cytotoxic activity. Additionally, compound 4 exhibited cytotoxic activity showing a certain degree of selectivity against cancer cell lines.

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Published

2017-10-12

Issue

Vol. 59 No. 3 (2015): Regular Issue

Section

Regular Articles

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