Antioxidant Potential of Liquidambar orientalis Mill. Fruit Extracts: A Total Phenolic Content and Radical Scavenging Evaluation

Authors

  • Deniz Soydemir Yildiz Technical University https://orcid.org/0009-0002-3332-5488
  • Mesut Bilgi Yildiz Technical University
  • Aysegul Peksel Yildiz Technical University

DOI:

https://doi.org/10.29356/jmcs.v70i1.2517

Keywords:

Anatolian sweetgum, antioxidant activity, free radical scavenging, ultrasound-assisted extraction

Abstract

Antioxidant compounds act as key defenders in preventing these harmful processes associated with oxidative stress by neutralizing the effects of free radicals and preserving cellular homeostasis. Synthetic antioxidants are generally more cost-effective than natural ones and are thus widely used across many industries. However, the potential toxicological risks associated with certain commonly used synthetic antioxidants have made the search for natural antioxidant alternatives inevitable. In this study, ethanol and water extracts of the fruits of Liquidambar orientalis Mill. (Anatolian sweetgum tree) were prepared using an ultrasound-assisted extraction method after the fruits were ground. The results showed that while both extracts had good phenolic and flavonoid amounts, the water extract had significant antioxidant activity. Water extract had nearly 92% activity in 2,2-diphenyl-1-picrylhydrazyl and 66% activity in N, N-dimethyl-1,4-phenylendiammoniumdichloride tests. And in β-carotene assay water extract had similar results to butylated hydroxyanisole. The results demonstrated that both extracts exhibited good radical scavenging activity and contained natural compounds with promising antioxidant potential. This suggests that fruits of L. orientalis might be used for its antioxidant potential and increase its value.

Downloads

Download data is not yet available.

Author Biographies

Deniz Soydemir, Yildiz Technical University

Department of Chemistry

Mesut Bilgi, Yildiz Technical University

Department of Chemistry

Aysegul Peksel, Yildiz Technical University

Department of Chemistry

References

1. Youssef, M.M.; Moharram, H.A.; Youssef, M.M. Alex. J. Fd. Sci. & Technol. 2014, 11, 31–42. DOI: https://doi.org/10.12816/0025348

2. Kozlov, A. V.; Javadov, S.; Sommer, N. Antioxidants. 2024, 13, 602. DOI:10.3390/antiox13050602

3. Niki, E. Food Funct. 2016, 7, 2156–2168. DOI:10.1039/C6FO00275G

4. Blagov, A. V.; Summerhill, V.I.; Sukhorukov, V.N.; Zhigmitova, E.B.; Postnov, A.Y.; Orekhov, A.N. Front. Pharmacol. 2024, 15. DOI:10.3389/fphar.2024.1378335.

5. Percival, M. Clinical Nutrition Insights. 1998, 31, 1–4.

6. Sehwag, S.; Das, M. Res. Rev. J. Food Sci. Technol. 2013, 2, 1–10.

7. Gulcin, İ. Arch. Toxicol. 2020, 94, 651–715. DOI:10.1007/s00204-020-02689-3.

8. Shahidi, F.; Zhong, Y. J. Funct. Foods 2015, 18, 757–781, DOI:10.1016/j.jff.2015.01.047.

9. Shahidi, F.; Ambigaipalan, P. J. Funct. Foods. 2015, 18, 820–897. DOI:10.1016/j.jff.2015.06.018.

10. Dinç Zor, Ş.; Bat, M.; Peksel, A.; Alpdoğan, G. J. Turk. Chem. Soc. Sect. A: Chemistry. 2017, 915–930. DOI:10.18596/jotcsa.324848.

11. Korkut, S.E.; Ahmetali, E.; Bilgi, M.; Karataş, Ö.; Yerli, Y.; Peksel, A.; Şener, M.K. Polyhedron. 2021, 197, 115045. DOI:10.1016/j.poly.2021.115045.

12. Gülçin, İ. Arch. Toxicol. 2012, 86, 345–391. DOI:10.1007/s00204-011-0774-2.

13. Arslan, M.B.; Şahin, H.T. Bar. Orm. Fak. Der. 2016, 18, 103–117.

14. İstek, A.; Hafızoğlu, H. Kastamonu Univ. Orman Fak. Derg. 2005, 5.

15. Saraç, N.; Şen, B. Ind. Crops Prod. 2014, 53, 60–64. DOI:10.1016/j.indcrop.2013.12.015.

16. Ulusoy, H.; Ceylan, Ş.; Peker, H. Polímeros. 2021, 31. DOI:10.1590/0104-1428.04221.

17. Baloglu, M.C.; Ozer, L.Y.; Pirci, B.; Zengin, G.; Uba, A.I.; Celik Altunoglu, Y. Chem. Biodivers. 2023, 20. DOI:10.1002/cbdv.202300291.

18. Okmen, G.; Turkcan, O.; Ceylan, O.; Gork, G. Afr. J. Tradit. Complement. Altern. Med. 2014, 11, 28. DOI:10.4314/ajtcam.v11i5.4.

19. Núñez, S.; Valero, M.S.; Mustafa, A.M.; Caprioli, G.; Maggi, F.; Gómez‐Rincón, C.; López, V. J. Sci. Food. Agric. 2025, 105, 3453–3462. DOI:10.1002/jsfa.14105.

20. Atasoy, K.S.; Bilgi, M.; Peksel, A. Period. Polytech. Chem. Eng. 2025, 69, 559–566. DOI:10.3311/PPch.41590.

21. Brand-Williams, W.; Cuvelier, M.E.; Berset, C. LWT-Food Sci. Technol. 1995, 28, 25–30. DOI:10.1016/S0023-6438(95)80008-5.

22. Fogliano, V.; Verde, V.; Randazzo, G.; Ritieni, A. J. Agric. Food Chem. 1999, 47, 1035–1040. DOI:10.1021/jf980496s.

23. Arnao, M.B.; Cano, A.; Acosta, M. Food Chem. 2001, 73, 239–244. DOI:10.1016/S0308-8146(00)00324-1.

24. Oyaizu, M. Jpn. J. Nutr. 1986, 44, 307–315, DOI:10.5264/eiyogakuzashi.44.307.

25. Decker, E.A.; Welch, B. J. Agric. Food Chem. 1990, 38, 674–677. DOI:10.1021/jf00093a019.

26. Bruni, R.; Muzzoli, M.; Ballero, M.; Loi, M.C.; Fantin, G.; Poli, F.; Sacchetti, G. Fitoterapia. 2004, 75, 50–61. DOI:10.1016/j.fitote.2003.07.009.

27. Slinkard, K.; Singleton, V.L. Am. J. Enol. Vitic. 1977, 28, 49–55. DOI:10.5344/ajev.1977.28.1.49.

28. Zhishen, J.; Mengcheng, T.; Jianming, W. Food Chem. 1999, 64, 555–559. DOI:10.1016/S0308-8146(98)00102-2.

29. Padmavati, M.; Sakthivel, N.; Thara, K.V.; Reddy, A.R. Phytochemistry. 1997, 46, 499–502. DOI:10.1016/S0031-9422(97)00325-7.

30. Christodoulou, M.C.; Orellana Palacios, J.C.; Hesami, G.; Jafarzadeh, S.; Lorenzo, J.M.; Domínguez, R.; Moreno, A.; Hadidi, M. Antioxidants. 2022, 11, 2213. DOI:10.3390/antiox11112213.

31. Çetinkaya, S.; Çınar Ayan, İ.; Süntar, İ.; Dursun, H.G. Nutr. Cancer. 2022, 74, 1457–1473. DOI:10.1080/01635581.2021.1952455.

32. Knez, E.; Kadac-Czapska, K.; Grembecka, M. Appl. Sci. 2025, 15, 5925, DOI:10.3390/app15115925.

33. Gulcin, İ.; Alwasel, S.H. Processes. 2022, 10, 132. DOI:10.3390/pr10010132.

34. Olszowy-Tomczyk, M.; Wianowska, D. Processes. 2025, 13, 3814. DOI:10.3390/pr13123814.

35. Lv, Q.; Long, J.; Gong, Z.; Nong, K.; Liang, X.; Qin, T.; Huang, W.; Yang, L. Nat. Prod. Commun. 2021, 16. DOI:10.1177/1934578X211027745.

36. Cerqueira, J.V.A.; Andrade, M.T. de; Rafael, D.D.; Zhu, F.; Martins, S.V.C.; Nunes-Nesi, A.; Benedito, V.; Fernie, A.R.; Zsögön, A. Plant Mol. Biol. 2023, 112, 213–223. DOI:10.1007/s11103-023-01362-4.

×

Downloads

Published

2026-07-07

Issue

Section

Regular Articles
x

Similar Articles

<< < 29 30 31 32 33 34 

You may also start an advanced similarity search for this article.

Loading...